About
Hello,
I'm YuYing
PhD researcher using sequencing and computational analysis in infectious disease research and drug discovery
PROJECTS
Early Phase Strategy for a First-in-Class Bispecific Antibody-Drug Conjugate Asset
Data-driven indication prioritization for NEOK001 (ROR1×B7-H3), a first-in-class bispecific ADC developed by NEOK Bio; integrating proteomic expression, market sizing, valuation, and competitive landscape analysis.
Genome-Wide Association Studies on Antifungal Resistance in Aspergillus fumigatus
Identifying genetic variations associated with
antifungal resistance across clinical and environmental A. fumigatus strains, by developing a genome-wide association analysis pipeline.
Clinical Trial Emulation: FLAURA Eligibility in Real-World NSCLC Data
Applying eligibility criteria from FLAURA, a landmark NSCLC trial, to the GENIE BPC NSCLC 2.0 real-world cohort to assess real-world generalizability.
Work in Progress
Identifying RNA-Binding Protein Targets in Mycobacterium Using Machine Learning
Building an ML classification pipeline to predict
binding sites and motifs for Srb, a novel RNA-binding protein, based on RIP-seq dataset. The supervised models tested were linear regression, random forest, and XGBoost.
Work in Progress | Paper submitted
Transcriptomic Analysis of a Novel RNA-Binding Protein Knockout in Mycobacterium
Characterizing transcriptomic profile shifts due to loss of Srb, a novel RNA-binding protein, in Mycobacterium tuberculosis using RNA-seq and differential expression analysis pipeline.